Estrogen receptor‐α partially mediates estrogen effect on muscle Hsp70 levels
نویسندگان
چکیده
منابع مشابه
Estrogen attenuates postexercise HSP70 expression in skeletal muscle.
Exercise has been demonstrated as a physiological inducer of heat shock protein (HSP)70. Many of the proposed signals of this response exhibit sexual dimorphism. Thus the present objectives were to determine whether HSP70 induction after exercise exhibits gender specificity and to elucidate the mechanisms underlying such a phenomenon. Postexercise HSP70 induction in skeletal muscle was greater ...
متن کاملEstrogen Attenuates Post-Exercise Hsp70 Expression in Skeletal Muscle Running Title: Sex-specific Hsp70 induction
Exercise has been demonstrated as a physiological inducer of Hsp70. Many of the factors associated with exercise proposed to signal this response demonstrate sexual dimorphism. Thus, the present objectives were to determine if Hsp70 induction following exercise exhibited gender-specificity and to elucidate the mechanisms underlying such a phenomenon. Post-exercise Hsp70 induction in skeletal mu...
متن کاملRapid estrogen receptor signaling mediates estrogen-induced inhibition of vascular smooth muscle cell proliferation.
OBJECTIVE The proliferation of vascular smooth muscle cells (VSMCs) plays a crucial role in vascular diseases, such as atherosclerosis and restenosis, after percutaneous coronary intervention. Many studies have shown that estrogen inhibits VSMC proliferation in response to vascular injury in the mouse carotid injury model. However, the mechanisms that mediate these effects remain unclear. Here,...
متن کاملEffect of cadmium on estrogen receptor levels and estrogen-induced responses in human breast cancer cells.
The effects of cadmium on estrogen receptor and other estrogen-regulated genes in the human breast cancer cell line MCF-7 were studied. Treatment of MCF-7 cells with 1 microM cadmium decreased the level of estrogen receptor 58%. Cadmium induced a parallel decrease in estrogen receptor mRNA (62%). Progesterone receptor levels increased 3.2-fold after cadmium treatment. This induction was blocked...
متن کاملEffect of Estrogen and Progesterone on Cytokines Levels at Different Time Intervals after Traumatic Brain Injury
Introduction: Following a traumatic brain injury (TBI), the excessive release of proinflammatory cytokines is major cause of cerebral edema that can cause permanent neuronal loss. This study examined the changes in brain concentrations of proinflammatory cytokines IL-1, IL-6, TNF-α and TGF- after different doses of estrogen or progesterone treatment in brain-injured rats at 6 and 24 h post...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2011
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.25.1_supplement.1060.2